Comparison of Activity in Other Available FC Products
Differences in the biochemical composition of plasma derived human fibrinogen concentrates1
Fibryga® 4g | Other Available FC | |
---|---|---|
Fibrinogen Antigen (g) | 3.0 | 3.3 |
Fibronectin (mg) | 2.1 | 140 |
VWF Antigen (U) | 30 | 570 |
FXIII Activity (U) | 585 | 165 |
Note: based on in vitro studies
Lower fibronectin and VWF antigen may contribute to increased safety, and higher FXIII levels may contribute to increased efficacy
1. Neisser-Svae et al. Differences in the biochemical composition of three plasma derived human fibrinogen concentrates. Thrombosis Research. 2021;205;44-46